Multicenter evaluation of a new enzyme immunoassay for detection of Clostridium difficile enterotoxin A
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چکیده
منابع مشابه
Evaluation of a new enzyme immunoassay for Clostridium difficile toxin A.
AIM To evaluate a new enzyme immunoassay (EIA) method for detection of Clostridium difficile toxin by comparing it to cytotoxicity assay. To investigate the nature of false negative and false positive EIA results by evaluating clinical and therapeutic parameters. METHODS 737 consecutive diarrhoeal specimens collected from patients clinically suspected of having C difficile colitis were tested...
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JOHN STEPHEN,* SUSAN C. REDMOND,* TIMOTHY J. MITCHELL,* JULIAN KETLEY,* DAVID C. A. CANDY,? DOUGLAS W. BURDONt and RICHARD DANIEL§ *Department of Microbiology. University of Birmingham, P.O. Box 363, Birmingham B15 ZTT, U.K., tlnstitute of Child Health, Francis Road, Edgbaston, Birmingham B16 8ET. U.K. , $Department of Microbiology, General Hospital, Steelhouse Lane, Birmingham B4 6NH U.K. , an...
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Clostridium difficile enterotoxin (D-1) was detected in 13 symptomatic and nine asymptomatic neonates in the neonatal intensive care unit by latex agglutination test but was not found in 18 healthy neonates in two other newborn nurseries. Environmental contamination in the intensive care unit may have been the cause. An association between the presence of enterotoxin and clinical symptoms is di...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1992
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.30.5.1085-1088.1992